In this article, we show that conolidine, a all-natural analgesic alkaloid Utilized in standard Chinese drugs, targets ACKR3, thus giving additional evidence of the correlation concerning ACKR3 and pain modulation and opening different therapeutic avenues for the therapy of Long-term pain. In this case, it enhances the Conolidine’s bioavailability, https://tinybookmarks.com/story19774573/everything-about-what-is-conolidine