Signal transducer and activator of transcription (STAT) is a unique protein family that binds to DNA. coupled with tyrosine phosphorylation signaling pathways. acting as a transcriptional regulator to mediate a variety of biological effects. Cerebral ischemia and reperfusion can activate STATs signaling pathway. https://www.roneverhart.com/L-Homme-Ideal-Cologne-by-Guerlain/