Heterosynaptic eLTD happens at synapses adjacent for the stimulated synapses. For example, stimulation of Schaffer collaterals in hippocampal CA1 brings about a persistent lower in GABAergic inhibition of CA1 pyramidal neurons (106). The system of eLTD at hippocampal inhibitory synapses seems to call for inhibition of adenylyl cyclase as well https://thca-flower15572.theideasblog.com/33285040/cannabis-an-overview