This mechanism is probably in the induction of hepatic microsomal enzymes that metabolize the antibiotic. If phenobarbital and doxycycline are administered concurrently, the clinical reaction to doxycycline need to be monitored closely. Phenytoin, sodium valproate, valproic acid: The impact of barbiturates around the metabolism of phenytoin appears to become variable. https://rowanwlxjv.blogvivi.com/28466579/the-fact-about-lsds-that-no-one-is-suggesting