Making predictions about DNA methylation status of the intercourse-determining location with the initiation of sex chromosome divergence is not really straightforward, as regulation of gene expression by DNA methylation is usually elaborate (Jaenisch and Fowl 2003). For example, hypermethylation of promoter regions is associated with a transcriptionally repressed state. https://forcefuckporn.skin/big-tits/japonese_feet_porn.html